MAT1A, 1-395aa, Human, His tag, E.coli from IBL- America

Supplier Page

Supplier Page from
IBL- America for
MAT1A, 1-395aa, Human, His tag, E.coli

Description

MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFκB and TNFα cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth